The ANCA (Anti Neutrophil Cytoplasmic Antibody) Screen without Titer - IFA test is a blood test primarily used in the diagnosis of autoimmune diseases that cause inflammation of blood vessels, or vasculitis, such as Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome.
Test NameANCA (Anti Neutrophil Cytoplasmic Antibody) Screen without Titer - IFA
Sample TypeBlood
Preparations RequiredNo special preparation is needed before this test. Always follow your healthcare provider's instructions.
Report Time6 hours
What is the ANCA Screen without Titer - IFA test?
ANCA stands for Antineutrophil Cytoplasmic Antibodies. These are autoantibodies—immune proteins that mistakenly target and react with a person's own tissues or organs—that are directed against proteins within neutrophils, a type of white blood cell. The ANCA screen test is used to detect and measure the presence of these antibodies in blood. Unlike the titer test, it doesn't measure the level of antibodies.
Why is the ANCA Screen without Titer - IFA test done?
This test is primarily ordered when a patient exhibits symptoms that suggest vasculitis, an inflammation of the blood vessels, especially when the patient has unexplained fever, weight loss, skin rashes, and nerve or organ damage. It's also used when a patient has symptoms of systemic vasculitis, including fatigue, muscle and joint pain, loss of appetite, and sinusitis or nosebleeds.
Home Sample Collection Process
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Book your convenient slot
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Sample Collection by Phlebotomist
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Reporting of the sample at lab
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Frequently Asked Questions
A blood sample is required for the ANCA Screen test. It's drawn from a vein in your arm and then sent to
a laboratory for analysis. Using indirect fluorescent antibody (IFA) testing, the lab checks for the
presence of ANCA in the blood.
In the ANCA Screen without Titer test, a positive result suggests the presence of ANCA in the blood,
which is associated with certain autoimmune diseases, particularly forms of vasculitis. However, a
positive result alone is not enough for a definitive diagnosis. Further testing, clinical findings, and
the patient's medical history need to be taken into account.
A positive result indicates the presence of ANCA in the blood. This could suggest an autoimmune disorder,
especially if the patient has symptoms of systemic vasculitis, like Wegener's granulomatosis,
microscopic polyangiitis, or Churg-Strauss syndrome. However, ANCA can also be present in people with
other autoimmune disorders or infections.
The risks related to the ANCA Screen without Titer - IFA test are minimal and mostly related to the blood
draw process. Potential complications may include slight pain or bruising at the site of the needle
insertion, fainting, or infection.
If the ANCA Screen test results are positive, your healthcare provider will discuss the findings with
you. Additional tests may be required to confirm a diagnosis and assess the severity of the condition.
There's no special preparation needed for the ANCA Screen test. Continue with your normal diet and any
medication unless your healthcare provider instructs otherwise.
Yes, certain medications may affect the results of the ANCA test. It's important to inform your
healthcare provider of any medications, including over-the-counter and prescription drugs, vitamins, and
herbal supplements that you are taking.
A positive ANCA Screen result can be instrumental in diagnosing vasculitis or another related condition,
leading to appropriate treatment. Monitoring ANCA can also be useful in assessing the effectiveness of
treatment and tracking disease activity.
This information provided is for educational purposes and should
not replace advice from a healthcare provider. Always consult with your healthcare provider for any questions or
concerns about your health.
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