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ANCA - IFA with Reflex Titers

The ANCA (Anti Neutrophil Cytoplasmic Antibody) - IFA with Reflex Titers test is a blood test utilized in the diagnosis of certain types of systemic vasculitis, such as Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome.


  • Test NameANCA (Anti Neutrophil Cytoplasmic Antibody) - IFA with Reflex Titers
  • Sample TypeBlood
  • Preparations RequiredNo special preparation is needed before this test. Always follow your healthcare provider's instructions.
  • Report Time24 hours

What is the ANCA - IFA with Reflex Titers test?

ANCA stands for Antineutrophil Cytoplasmic Antibodies. These are autoantibodies—immune proteins that mistakenly target and react with a person's own tissues or organs—that target proteins within neutrophils, a type of white blood cell. The ANCA test detects and measures the amount of ANCA in the blood. If the initial IFA (Indirect Fluorescent Antibody) test is positive, reflex titer testing is done to determine the level of these antibodies.

Why is the ANCA - IFA with Reflex Titers test performed?

The ANCA test is primarily used to help diagnose diseases that cause inflammation of the blood vessels (vasculitis), particularly when a person has signs and symptoms that suggest systemic vasculitis. It may also help monitor the effectiveness of treatment in a person diagnosed with a condition associated with ANCA.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The test requires a blood sample, which is typically drawn from a vein in your arm. The blood sample is then sent to a lab, where it's analyzed for the presence of ANCA. If the test detects ANCA, further tests are performed to determine the level of these antibodies.

A positive result suggests the presence of ANCA and is associated with systemic vasculitis and other related conditions. The pattern and type of ANCA (C-ANCA or P-ANCA) can give additional information about which condition may be present. It's important to note that while this test can aid in diagnosis, other tests and clinical findings are often necessary to confirm a specific diagnosis.

A positive result means that the test has detected ANCA in the blood. This may suggest an autoimmune disorder, particularly systemic vasculitis such as Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome. However, ANCA can also be detected in people with other autoimmune disorders, liver disease, inflammatory bowel disease, and infections.

The risks are minimal and are related to the blood draw process. These can include slight pain or bruising at the injection site. In very rare cases, there can be complications like fainting or infection at the puncture site.

If the test results are positive, your healthcare provider will discuss the results with you and may order additional tests to confirm a diagnosis and to determine the severity of the disease. If the test is negative but suspicion for vasculitis remains high, further testing may be pursued.

There is no special preparation needed for the ANCA test. You can continue with your normal diet and medications unless otherwise instructed by your healthcare provider.

Certain medications may affect the results of the ANCA test. It is important to inform your healthcare provider of any medications, supplements, or treatments you are receiving.

If the ANCA test result is positive and you have symptoms of vasculitis, your healthcare provider will likely diagnose you with a form of vasculitis and will begin appropriate treatment. If you are being treated for vasculitis, a decrease in ANCA levels can indicate that the treatment is working, while an increase may indicate a flare-up of the disease.

Always consult with your healthcare provider for any concerns or questions regarding your health.

ANCA (Anti Neutrophil Cytoplasmic Antibody) - IFA with reflex titers
₹ 2500
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Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet