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AMPA-GluR1 & R2

AMPA-GluR1 and R2 are subunits of the AMPA receptor, a type of glutamate receptor found in the central nervous system. Glutamate is the primary excitatory neurotransmitter in the brain, and AMPA receptors are involved in fast synaptic transmission. These receptors play a significant role in synaptic plasticity, which is crucial for learning and memory. Changes in the function or expression of AMPA receptors have been implicated in several neurological and psychiatric disorders, including epilepsy, schizophrenia, depression, and Alzheimer's disease. Assessing the levels of AMPA-GluR1 and R2 can provide valuable information regarding the neurotransmission processes in the brain and help diagnose certain neurological conditions.


  • Test NameAMPA-GluR1 & R2
  • Sample TypeBlood (serum)
  • Preparations RequiredNo special preparations are required before this test. Regular medications can be taken unless instructed otherwise by the doctor.
  • Report Time24 hours

What are AMPA-GluR1 and R2?

AMPA-GluR1 and R2 are subunits of the AMPA receptor, which is a type of glutamate receptor. Glutamate receptors are involved in transmitting signals in the brain and play an essential role in learning, memory, and overall brain function.

Why is the AMPA-GluR1 & R2 test done?

The test is done to evaluate the levels of AMPA-GluR1 and R2 in the blood. Changes in the levels of these receptor subunits can be associated with various neurological and psychiatric disorders such as Alzheimer's disease, epilepsy, and schizophrenia. The test helps in diagnosing and monitoring these conditions.

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

Abnormal levels of AMPA-GluR1 and R2 could indicate alterations in glutamate receptor function, which may be associated with neurological disorders. High levels might indicate increased excitatory signaling, whereas low levels could imply reduced signaling. Both scenarios can be associated with different neurological conditions.

Treatment depends on the underlying condition causing the abnormal levels. Medications and interventions to manage symptoms or target specific mechanisms may be recommended by the doctor based on the diagnosis.

There are minimal risks associated with the blood test, such as bruising or infection at the needle site. However, these are common risks associated with any blood draw.

A healthcare professional will collect a blood sample from a vein, usually in your arm.

Certain medications, especially those acting on the central nervous system, may affect AMPA receptor function and thus influence AMPA-GluR1 and R2 levels. It’s important to inform your doctor of all medications you are taking.

While the impact of lifestyle on AMPA receptor subunits is not entirely clear, factors such as stress, diet, and exercise can influence brain chemistry and may have an indirect effect on AMPA-GluR1 and R2 levels.

Symptoms can vary widely depending on the underlying disorder but may include memory loss, seizures, mood changes, difficulty concentrating, and other cognitive or behavioral issues.

The doctor may order additional tests, such as MRI scans, EEG, or other blood tests, to provide more information about your neurological health.

The frequency of testing depends on your health status and the doctor's recommendations, usually based on the condition being monitored or suspected.

Various factors, including medications, stress, neurological disorders, and genetic factors, can affect the levels of AMPA-GluR1 and R2.

Consult a neurologist or psychiatrist if your AMPA-GluR1 and R2 levels are abnormal, as they specialize in neurological and mental health disorders.

Yes, changes in AMPA receptors, including AMPA-GluR1 and R2, have been implicated in the pathophysiology of Alzheimer's disease.

Some studies suggest that certain nutrients and supplements may influence glutamate receptor function, but more research is needed to understand the specific effects on AMPA-GluR1 and R2 levels.

AMPA-GluR1 and R2 levels can provide insights into the functioning of glutamate receptors in the brain, which play an essential role in learning, memory, and cognition. Abnormal levels of these receptor subunits may be associated with various neurological and psychiatric disorders. Understanding these levels, along with other diagnostic tests and clinical evaluation, can help in the diagnosis and management of these conditions.

AMPA-GluR1 & R2
₹ 20950
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