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Ammonia - Plasma

The Ammonia - Plasma test is used to measure the levels of ammonia in the blood. Ammonia is a byproduct produced when protein is broken down in the body. The liver converts ammonia into urea, a less toxic substance, which is then excreted in the urine. When the liver is not functioning properly, ammonia levels can rise, leading to hyperammonemia. Elevated ammonia levels can be toxic, especially to the brain, and can cause confusion, lethargy, and even coma or death in severe cases. Therefore, testing ammonia levels is important in evaluating liver function and diagnosing liver diseases.


  • Test NameAmmonia - Plasma
  • Sample TypeBlood (Plasma)
  • Preparations RequiredAvoid eating high-protein meals before the test. Exercise or muscle activity should also be avoided just before the test. The healthcare provider drawing your blood will ensure that the tourniquet is not on your arm for too long to avoid affecting the result. Smoking should also be avoided before the test.
  • Report Time4 hours

What is the Ammonia - Plasma test?

The Ammonia - Plasma test measures the concentration of ammonia in the blood. Ammonia is produced when proteins are broken down by the body. The liver normally converts ammonia into urea, which is then excreted through the urine.

Why is the Ammonia - Plasma test performed?

The test is performed to evaluate liver function, especially in cases of suspected liver disease or damage. It's also used to diagnose and manage conditions that cause elevated blood ammonia levels, such as Reye’s syndrome or hepatic encephalopathy.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

A healthcare provider will take a blood sample from a vein in your arm using a small needle. The procedure is quick and usually only causes mild discomfort.

Normal levels of ammonia vary, but typically fall between 15 to 45 µg/dL. Elevated levels of ammonia may indicate liver disease, Reye’s syndrome, or another condition affecting ammonia metabolism. Low levels are generally not considered problematic.

High levels of ammonia can be toxic to the body, especially the brain. It's important to identify the cause of elevated ammonia levels. Treatment will depend on the underlying cause and may include medications, dietary changes, and in some cases, procedures or surgeries.

Avoid high-protein meals and excessive muscle activity before the test. Smoking should also be avoided. Make sure to follow any additional instructions given by your healthcare provider.

Yes, certain medications such as diuretics, antibiotics, valproic acid, and others can affect ammonia levels. Inform your doctor of all medications you are taking.

Symptoms of high ammonia levels include confusion, fatigue, changes in behavior, slurred speech, muscle weakness, and nausea. In severe cases, it can cause coma or death.

In cases where liver disease is the cause of increased ammonia, a low-protein diet may be recommended to reduce the amount of ammonia produced.

Hepatic encephalopathy is a condition in which liver disease affects brain function, leading to confusion, lethargy, and personality changes. It is often associated with high levels of ammonia in the blood.

Yes, the test is used in newborns to detect metabolic disorders that can cause high ammonia levels, such as urea cycle disorders.

Risks are minimal but may include bruising, infection, or light-headedness.

No, while liver disease is a common cause, other conditions such as metabolic disorders, Reye’s syndrome, and severe heart failure can also cause elevated ammonia levels.

If your ammonia levels are abnormal, it's recommended to consult a hepatologist or a gastroenterologist.

The frequency of testing depends on the underlying condition and its management. Your doctor will provide guidance on how often you need to be tested.

TheAmmonia - Plasma test is crucial for evaluating liver function and diagnosing conditions that can cause high blood ammonia levels. Understanding and monitoring these levels can be essential in managing your health, especially if you have a liver disorder or other conditions associated with ammonia metabolism. Always consult your doctor for detailed information and advice regarding your health and any necessary tests or treatments.

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