Amino Levulinic Acid 5 (ALA) Spot Urine Test - Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : Its recommended to avoid consuming foods high in tyramine such as red wine, cheese, and smoked meats 24 hours prior to the test. Also, inform your doctor if you are taking any medications, as some of them, such as barbiturates and oral contraceptives, can affect the test results.

₹ 4000


Delta-aminolevulinic acid (ALA) is an essential compound produced in the liver as a precursor to porphyrins, which are crucial for hemoglobin function. Hemoglobin is the protein in red blood cells that carries oxygen. The Amino Levulinic Acid 5 - ALA - Spot Urine test measures the levels of ALA in a single urine sample. This test is particularly vital in diagnosing and monitoring conditions related to the synthesis of porphyrin and heme, such as porphyria. It is also useful in monitoring lead exposure. The test is less cumbersome than the 24-hour urine collection method and provides useful information.

Test Name Amino Levulinic Acid 5 - ALA - Spot Urine
Sample Type Spot Urine
Preparations Required It’s recommended to avoid consuming foods high in tyramine such as red wine, cheese, and smoked meats 24 hours prior to the test. Also, inform your doctor if you are taking any medications, as some of them, such as barbiturates and oral contraceptives, can affect the test results.
Report Time 4 days
Price in Hyderabad ₹ 4000

What is the Amino Levulinic Acid 5 - ALA - Spot Urine test?

This test measures the levels of delta-aminolevulinic acid (ALA) in a single urine sample. ALA is an important compound in the body involved in the synthesis of heme, a vital component of hemoglobin in red blood cells.

Why is this test performed?

This test is used to help diagnose disorders related to heme synthesis, such as porphyria. It's also used to monitor exposure to lead, as lead can disrupt heme synthesis and lead to elevated levels of ALA in the urine.

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How is the sample collected?

A single urine sample is collected in a clean container. You will urinate into the container, and the sample will be sent to the laboratory for analysis.

What do the test results indicate?

Elevated levels of ALA in the urine can indicate a disorder in heme synthesis, such as porphyria, or exposure to lead. Normal levels of ALA may vary, but significantly elevated levels require further investigation.

How should I prepare for this test?

You should avoid foods high in tyramine for 24 hours before the test. Inform your doctor of any medications you are taking, as certain medications can affect ALA levels.

Can medication affect my ALA levels?

Yes, certain medications such as barbiturates and oral contraceptives can affect ALA levels. It is essential to inform your doctor of all medications you are taking before the test.

What are the symptoms of heme synthesis disorders?

Symptoms of heme synthesis disorders, such as porphyria, include abdominal pain, muscle weakness, sensitivity to sunlight, and neurological issues.

What is the difference between spot urine and 24-hour urine collection?

Spot urine collection involves providing a single urine sample at a specific point in time, whereas a 24-hour urine collection requires collecting all urine produced over a 24-hour period. The spot urine test is more convenient but may not be as comprehensive as the 24-hour test.

Who should get this test?

Individuals experiencing symptoms like abdominal pain, muscle weakness, or neurological issues, or who have been exposed to lead should consider this test.

What is the next step if my test results are abnormal?

If your ALA levels are elevated, it is important to consult a doctor, who may recommend further testing to determine the cause of the elevated levels.

What are the treatment options for heme synthesis disorders?

Treatment options depend on the specific disorder and its severity. For porphyria, management may include avoiding triggers, taking medications to regulate heme synthesis, or undergoing procedures to remove excess porphyrins from the blood.

How does lead exposure affect ALA levels?

Lead can disrupt enzymes involved in heme synthesis, causing an accumulation of ALA in the blood, which is then excreted in the urine.

Can I take this test if I am pregnant?

It is essential to inform your doctor if you are pregnant, as pregnancy can affect the interpretation of test results.

Are there any risks associated with this test?

There are no significant risks associated with providing a urine sample. The test is non-invasive and typically has no side effects.

Which doctor should I consult for abnormal ALA levels?

If your ALA levels are abnormal, it’s recommended to consult a hematologist or a doctor specializing in metabolic disorders.

After your test, the results will help your doctor understand if there are any issues with your body's ability to synthesize heme or if there has been exposure to lead. This information is crucial for the appropriate management of any underlying conditions.

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