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17 Alpha Hydroxy Progesterone Test - Requirements, Normal Range | Sprint Diagnostics

17-Alpha-Hydroxyprogesterone (17-OHP) neonatal screening is a test typically conducted on newborns to detect congenital adrenal hyperplasia (CAH), a group of genetic disorders that affect the adrenal glands. These disorders can lead to abnormal growth and development and, in severe cases, life-threatening adrenal crisis.

  • Test Name 17 - Alpha-Hydroxyprogesterone (Neonatal Screening)
  • Sample Type Blood Spot (Heel prick in neonates)
  • Preparations Required No specific preparation is required
  • Report Time 4 days

Home Sample Collection Process

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Reporting of the sample at lab
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Frequently Asked Questions

The 17-OHP neonatal screening test is crucial for early detection of CAH in newborns, enabling timely intervention and preventing severe complications.

The test requires a blood spot sample, typically obtained through a heel prick in newborns.

No, fasting is not required for neonatal screening tests.

No specific preparation is required for this test.

This test is typically conducted within 48-72 hours of birth, or as advised by your healthcare provider.

The test measures the level of 17-Alpha Hydroxyprogesterone (17-OHP) in the blood, an important precursor in cortisol synthesis.

Screening for CAH is usually done once shortly after birth. If initial results are elevated, repeat testing may be required.

Normal values for newborns typically range from 5-90 ng/dL, but it may vary slightly depending on the lab and method used.

Ensure your healthcare provider is aware of any medications or treatments your newborn is receiving, as some may influence the results.

Modifiable Factors: Certain medications can affect the results.

Nonmodifiable Factors: The infant's weight and age at the time of screening may affect 17-OHP levels.

If your newborn's test results are abnormal, you should consult a pediatric endocrinologist.

Abnormal 17-OHP levels often require management of the underlying condition, typically CAH. This can involve medications, regular monitoring, and in some cases, surgery.

Abnormal results might indicate CAH or other adrenal disorders. Your healthcare provider will guide you on further steps, which may include additional testing.

Yes, certain medications can affect 17-OHP levels. Always inform your healthcare provider about any medication your newborn is receiving.

The 17-OHP Test is a reliable screening tool for CAH in newborns, but it should be followed up with confirmatory tests if results are abnormal.

Low 17-OHP levels are usually normal and not a cause for concern. However, always consult your healthcare provider if you have any concerns.

Screening and early detection are the best prevention methods for conditions that might cause abnormal 17-OHP levels, such as CAH.

Your healthcare provider will discuss the test results with you. If the results are abnormal, further testing or consultations with specialists may be needed.

Yes, the age of the newborn at the time of the test can affect the 17-OHP levels, which is why it's usually performed within 48-72 hours of birth.

Yes, the weight of the newborn at the time of testing can affect the 17-OHP levels.

Neonatal screening for 17-OHP is an essential step in the early detection of conditions like CAH. This allows for timely intervention, which can significantly improve a child's quality of life and prevent severe complications. As a parent or caregiver, ensure that you communicate effectively with your healthcare provider, ask questions if you have any doubts, and follow their advice for the best health outcomes for your child.

Neonatal Screening (17- Alpha Hydroxyprogesterone)
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