17 Alpha Hydroxy Progesterone Test - Requirements, Normal Range | Sprint Diagnostics

Patient Preparing : No specific preparation is required

₹ 450

17-Alpha-Hydroxyprogesterone (17-OHP) neonatal screening is a test typically conducted on newborns to detect congenital adrenal hyperplasia (CAH), a group of genetic disorders that affect the adrenal glands. These disorders can lead to abnormal growth and development and, in severe cases, life-threatening adrenal crisis.

Test Name 17 - Alpha-Hydroxyprogesterone (Neonatal Screening)
Sample Type Blood Spot (Heel prick in neonates)
Preparations Required No specific preparation is required
Report Time 4 days
Price ₹ 450

Why is this test important for newborns?

The 17-OHP neonatal screening test is crucial for early detection of CAH in newborns, enabling timely intervention and preventing severe complications.

What sample type is required for this test?

The test requires a blood spot sample, typically obtained through a heel prick in newborns.

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Is fasting required for this test?

No, fasting is not required for neonatal screening tests.

Is there any specific preparation needed for this test?

No specific preparation is required for this test.

When should my newborn get this test?

This test is typically conducted within 48-72 hours of birth, or as advised by your healthcare provider.

What does this test measure?

The test measures the level of 17-Alpha Hydroxyprogesterone (17-OHP) in the blood, an important precursor in cortisol synthesis.

How often should my newborn be tested?

Screening for CAH is usually done once shortly after birth. If initial results are elevated, repeat testing may be required.

What are the normal values for this test?

Normal values for newborns typically range from 5-90 ng/dL, but it may vary slightly depending on the lab and method used.

What precautions should I take before my newborn's test?

Ensure your healthcare provider is aware of any medications or treatments your newborn is receiving, as some may influence the results.

What factors can affect the test results?

Modifiable Factors: Certain medications can affect the results.

Nonmodifiable Factors: The infant's weight and age at the time of screening may affect 17-OHP levels.

Which doctor should I consult if the test results are abnormal?

If your newborn's test results are abnormal, you should consult a pediatric endocrinologist.

How can abnormal 17-OHP levels be managed?

Abnormal 17-OHP levels often require management of the underlying condition, typically CAH. This can involve medications, regular monitoring, and in some cases, surgery.

What if my newborn's test results are abnormal?

Abnormal results might indicate CAH or other adrenal disorders. Your healthcare provider will guide you on further steps, which may include additional testing.

Can certain medications affect the test results?

Yes, certain medications can affect 17-OHP levels. Always inform your healthcare provider about any medication your newborn is receiving.

How reliable is the neonatal 17-OHP Test?

The 17-OHP Test is a reliable screening tool for CAH in newborns, but it should be followed up with confirmatory tests if results are abnormal.

What should I do if my newborn's 17-OHP levels are low?

Low 17-OHP levels are usually normal and not a cause for concern. However, always consult your healthcare provider if you have any concerns.

Can I prevent abnormal 17-OHP levels in my newborn?

Screening and early detection are the best prevention methods for conditions that might cause abnormal 17-OHP levels, such as CAH.

What happens after the test?

Your healthcare provider will discuss the test results with you. If the results are abnormal, further testing or consultations with specialists may be needed.

Can the test results be influenced by the newborn's age?

Yes, the age of the newborn at the time of the test can affect the 17-OHP levels, which is why it's usually performed within 48-72 hours of birth.

Can the test results be influenced by the newborn's weight?

Yes, the weight of the newborn at the time of testing can affect the 17-OHP levels.

Neonatal screening for 17-OHP is an essential step in the early detection of conditions like CAH. This allows for timely intervention, which can significantly improve a child's quality of life and prevent severe complications. As a parent or caregiver, ensure that you communicate effectively with your healthcare provider, ask questions if you have any doubts, and follow their advice for the best health outcomes for your child.

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