Alpha Feto Protein (AFP) - Cerebrospinal Fluid (CSF) - Price, Normal Range | Sprint Diagnostics Hyderabad

The measurement of AFP in the cerebrospinal fluid (CSF) is often used in the diagnostic evaluation of certain types of brain and spinal cord tumors, particularly those derived from germ cells. Elevated levels of AFP in the CSF can be suggestive of these types of tumors.

The test is performed on a sample of cerebrospinal fluid. This is typically obtained through a lumbar puncture (spinal tap) procedure, where a needle is inserted into the lower part of the spinal column to withdraw a small amount of CSF for testing.

A healthcare provider might order an AFP test on CSF if a patient presents with neurological symptoms that suggest the presence of a central nervous system tumor. The test can provide valuable information to help diagnose and classify the tumor.

Results are typically reported in concentration (like nanograms per milliliter). High levels of AFP in CSF may suggest the presence of a germ cell tumor in the central nervous system.

High levels of AFP in CSF can suggest the presence of a germ cell tumor, such as a yolk sac tumor or a mixed germ cell tumor, in the brain or spinal cord. It's important to note that AFP is not solely specific to these conditions and elevated levels can also be seen in other situations.

Certain medications and conditions can affect the level of AFP. In the context of CSF, elevated levels of AFP are most often associated with the presence of germ cell tumors, but can also be affected by the presence of other types of cancers or non-cancerous conditions.

While a lumbar puncture is generally safe, it does come with a small risk of complications. These can include headache, infection, bleeding, and, in rare cases, damage to the spinal cord or nerves.

There's no special preparation required for an AFP test. However, because it involves a lumbar puncture, you may be asked to fast for a few hours before the procedure. You should also inform your doctor about any medications you're taking as some could affect the procedure or test results.

After the test, you'll likely need to rest flat on your back for a short while to reduce the risk of headache. You should avoid strenuous activities for the rest of the day. You can resume your regular activities and diet after the procedure, unless instructed otherwise by your healthcare provider.

The turnaround time for AFP in CSF is typically 2-3 days. However, the exact timing may depend on the laboratory performing the test.

The frequency of testing would depend on the individual patient's symptoms and medical condition. If a germ cell tumor is suspected, your healthcare provider may recommend regular testing to monitor for changes in AFP levels.

Yes, in addition to AFP, other proteins can be measured in CSF to help determine the cause of neurological symptoms. These may include Beta-2 Transferrin, IgG Index, and others, depending on the condition being investigated.

Other tests often performed in conjunction with AFP testing in CSF include cell count, glucose, protein levels, and cultures to check for infection. Additionally, other tumor markers like Beta-HCG may be measured.

This information should be interpreted in the context of the patient's symptoms, medical history, and other test results. It is always advised to discuss these test results and any concerns with your healthcare provider.