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Alpha 2 Macroglobulin Test - Price, Normal Range | Sprint Diagnostics Hyderabad

Alpha 2 Macroglobulin (A2M) is a large plasma protein found in the blood. It is an important component of the immune system, serving as a broad-spectrum proteinase inhibitor.


  • Test Name Alpha 2 Macroglobulin
  • Sample Type Blood
  • Preparations Required No special preparation is needed before this test.
  • Report Time 2 days

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

Alpha 2 Macroglobulin (A2M) is a large plasma protein produced by the liver. It acts as a major inhibitor of many different types of proteolytic enzymes (proteases), which are enzymes that break down proteins. It is involved in many physiological processes, including blood clotting and inflammation.

The Alpha 2 Macroglobulin test measures the level of A2M in the blood. It is often used as a marker for various conditions like liver disease, nephrotic syndrome, and certain types of cancer. A2M levels can also be used to assess the body's overall protein status and nutritional state.

The Alpha 2 Macroglobulin test is performed using a blood sample, which is obtained through a simple blood draw. The blood sample is then sent to a laboratory for analysis.

A healthcare provider may order an Alpha 2 Macroglobulin test when a person has symptoms such as swelling, fatigue, and changes in weight, which may suggest a protein imbalance or a liver condition. The test can also be useful in evaluating a person's overall nutritional status and in the diagnosis of certain cancers.

Test results are generally reported in milligrams per deciliter (mg/dL). Normal levels of Alpha 2 Macroglobulin in the blood are typically between 160 and 330 mg/dL. However, these ranges can vary depending on the lab. Higher levels of A2M can indicate conditions such as liver disease, inflammation, and cancer, while lower levels can be seen in conditions such as malnutrition and nephrotic syndrome.

Certain factors can affect A2M levels, including age, nutritional status, and the presence of underlying conditions such as liver disease, cancer, and kidney disorders. Certain medications may also affect A2M levels.

High levels of Alpha 2 Macroglobulin can be associated with conditions that cause an increase in protein production, such as acute and chronic inflammatory conditions, malignancies, and liver disease. It can also be a sign of conditions that decrease the removal of proteins from the body, such as certain kidney disorders.

The Alpha 2 Macroglobulin test is a common blood test and is generally safe. There may be minor risks associated with blood drawing, including slight pain or bruising at the injection site, fainting, or the risk of an infection.

Yes, Alpha 2 Macroglobulin levels can change in response to inflammation, infection, injury, or malnutrition. Levels typically rise in response to an acute event or a state of inflammation and can decrease in conditions that lead to a loss of proteins from the body, such as nephrotic syndrome.

Alpha 2 Macroglobulin levels are largely controlled by your body's overall health status. Eating a balanced diet and maintaining a healthy lifestyle can support your body's protein balance, but it may not directly affect A2M levels. If your A2M levels are abnormal, it's important to work with your healthcare provider to identify the underlying cause and develop a treatment plan.

No, the Alpha 2 Macroglobulin test is a laboratory test that requires a blood sample to be drawn by a healthcare professional.

Yes, the Alpha 2 Macroglobulin test can be used to monitor the progression of certain diseases. Elevated levels may indicate an active disease state, while decreasing levels may indicate response to treatment.

If your Alpha 2 Macroglobulin levels are abnormal, your healthcare provider may order additional tests to help determine the cause. This could include tests for specific conditions like liver disease or cancer, or tests to assess your overall protein and nutritional status.

Most medications do not interfere with the test, but some medications can affect the level of proteins in your blood. It's important to discuss all medications you're taking with your healthcare provider before the test.

The frequency of the Alpha 2 Macroglobulin test depends on your individual health situation. Your healthcare provider will recommend how often you should have this test based on your symptoms, medical history, and whether you're monitoring a known condition.

Alpha 2 Macroglobulin
₹ 3500
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  • 5KM from Shaikpet