ALL Cytogenetics 1 Test, Price, Normal Range | Sprint Diagnostics Hyderabad

Patient Preparing : No fasting required. It is important to inform the doctor of any medications or supplements that are being taken.

₹ 15900

ALL Cytogenetics 1 is a combination of diagnostic tests used for the evaluation of patients suspected to have Acute Lymphoblastic Leukemia (ALL), which is a type of cancer that affects the white blood cells. This comprehensive testing panel includes karyotyping and Fluorescence In Situ Hybridization (FISH) to assess for chromosomal abnormalities commonly associated with ALL, such as BCR-ABL1, TEL-AML1, MLL, and E2A rearrangements.

Karyotyping is a technique used to visualize chromosomes in a cell. By staining and photographing the chromosomes, the laboratory can analyze their number and structure. FISH, on the other hand, is a specialized technique that uses fluorescent probes to detect specific DNA sequences within chromosomes, allowing for the identification of chromosomal rearrangements.

Test Name ALL Cytogenetics 1 (Karyotyping + FISH for BCR-ABL1 + TEL- AML1 + MLL + E2A rearrangement)
Sample Type Bone Marrow or Blood
Preparations Required No fasting required. It is important to inform the doctor of any medications or supplements that are being taken.
Report Time 12 Days for Karyotype & 5 Days for FISH
Price in Hyderabad ₹ 15900

What is Acute Lymphoblastic Leukemia (ALL)?

ALL is a form of blood cancer characterized by the overproduction of immature white blood cells, known as lymphoblasts or blasts. These immature cells crowd the bone marrow, preventing it from making healthy blood cells.

Why is the ALL Cytogenetics 1 panel important?

This panel is critical for the diagnosis, prognosis, and management of ALL. It helps in detecting chromosomal abnormalities that are associated with ALL, which can aid in tailoring the treatment plan.

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Is fasting required for this test?

No, fasting is not required for the ALL Cytogenetics 1 panel.

When should one get this test done?

This test is usually ordered when a patient has signs and symptoms that suggest ALL, such as fatigue, fever, and easy bruising or bleeding. It is also done when other blood tests show abnormal results that are suggestive of leukemia.

What information does the ALL Cytogenetics 1 panel provide?

This panel provides detailed information about the chromosomal structure and the presence of specific gene rearrangements in the cells. This information can help in diagnosing ALL, determining its subtype, and guiding treatment decisions.

How often should this test be done?

This test is generally done at the time of diagnosis. It may be repeated if the patient relapses or if monitoring for specific genetic changes is necessary during treatment.

What are the normal values for this test?

In a normal result, no abnormal chromosomal changes or rearrangements should be present. However, the presence of certain abnormalities can indicate ALL or its subtype.

What precautions need to be taken before taking this test?

There are no specific precautions that need to be taken before the test, but it's important to inform the doctor of any medications or supplements you are taking.

What are the factors that can affect the levels of this test?

The presence of leukemia cells, genetic mutations, or treatment can affect the results of this test.

Are there any risks associated with this test?

The risks are similar to those of a regular blood draw, including pain, bleeding, or infection at the puncture site.

Which doctor should be consulted in case of abnormal values?

In case of abnormal values, it is crucial to consult a hematologist or oncologist who specializes in blood disorders and cancer.

How is the sample collected for this test?

A sample of blood is drawn from a vein, typically in the arm. In some cases, a bone marrow sample may be taken, which involves inserting a needle into the hip bone to collect a small amount of bone marrow tissue.

How does this test affect treatment decisions?

The results of the ALL Cytogenetics 1 panel can guide doctors in making treatment decisions, including the selection of specific therapies that target the genetic abnormalities identified.

Can lifestyle or dietary changes impact the results or management of ALL?

While lifestyle and dietary changes may contribute to the overall health of a patient with ALL, they are unlikely to significantly impact the results of the genetic tests or the course of the disease.

What is the role of FISH in the ALL Cytogenetics 1 panel?

FISH is used to detect specific genetic changes and chromosomal rearrangements that are too small to be seen with karyotyping. It helps in identifying specific subtypes of ALL, which can be critical for prognosis and treatment.

By analyzing the chromosomal structure and gene rearrangements, the ALL Cytogenetics 1 panel provides essential information for the diagnosis and management of Acute Lymphoblastic Leukemia. It's an indispensable tool that helps doctors to tailor treatment plans according to the genetic profile of the leukemia. If you or a loved one has been diagnosed with ALL or has symptoms suggestive of this disease, this panel could be a crucial step in getting the most effective treatment. It's important to have open communication with the doctor and follow the recommended course of action.

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