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Lab Test

ALL Cytogenetics 1

ALL Cytogenetics 1 is a combination of diagnostic tests used for the evaluation of patients suspected to have Acute Lymphoblastic Leukemia (ALL), which is a type of cancer that affects the white blood cells. This comprehensive testing panel includes karyotyping and Fluorescence In Situ Hybridization (FISH) to assess for chromosomal abnormalities commonly associated with ALL, such as BCR-ABL1, TEL-AML1, MLL, and E2A rearrangements.


Karyotyping is a technique used to visualize chromosomes in a cell. By staining and photographing the chromosomes, the laboratory can analyze their number and structure. FISH, on the other hand, is a specialized technique that uses fluorescent probes to detect specific DNA sequences within chromosomes, allowing for the identification of chromosomal rearrangements.

  • Profile Name: ALL Cytogenetics 1
  • Sample Type: Bone Marrow or Blood
  • Preparations Required: No fasting required. It is important to inform the doctor of any medications or supplements that are being taken.
  • Report Time: 12 Days for Karyotype & 5 Days for FISH

What is Acute Lymphoblastic Leukemia (ALL)?

ALL is a form of blood cancer characterized by the overproduction of immature white blood cells, known as lymphoblasts or blasts. These immature cells crowd the bone marrow, preventing it from making healthy blood cells.

Why is the ALL Cytogenetics 1 panel important?

This panel is critical for the diagnosis, prognosis, and management of ALL. It helps in detecting chromosomal abnormalities that are associated with ALL, which can aid in tailoring the treatment plan.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

No, fasting is not required for the ALL Cytogenetics 1 panel.

This test is usually ordered when a patient has signs and symptoms that suggest ALL, such as fatigue, fever, and easy bruising or bleeding. It is also done when other blood tests show abnormal results that are suggestive of leukemia.

This panel provides detailed information about the chromosomal structure and the presence of specific gene rearrangements in the cells. This information can help in diagnosing ALL, determining its subtype, and guiding treatment decisions.

This test is generally done at the time of diagnosis. It may be repeated if the patient relapses or if monitoring for specific genetic changes is necessary during treatment.

In a normal result, no abnormal chromosomal changes or rearrangements should be present. However, the presence of certain abnormalities can indicate ALL or its subtype.

There are no specific precautions that need to be taken before the test, but it's important to inform the doctor of any medications or supplements you are taking.

The presence of leukemia cells, genetic mutations, or treatment can affect the results of this test.

The risks are similar to those of a regular blood draw, including pain, bleeding, or infection at the puncture site.

In case of abnormal values, it is crucial to consult a hematologist or oncologist who specializes in blood disorders and cancer.

A sample of blood is drawn from a vein, typically in the arm. In some cases, a bone marrow sample may be taken, which involves inserting a needle into the hip bone to collect a small amount of bone marrow tissue.

The results of the ALL Cytogenetics 1 panel can guide doctors in making treatment decisions, including the selection of specific therapies that target the genetic abnormalities identified.

While lifestyle and dietary changes may contribute to the overall health of a patient with ALL, they are unlikely to significantly impact the results of the genetic tests or the course of the disease.

FISH is used to detect specific genetic changes and chromosomal rearrangements that are too small to be seen with karyotyping. It helps in identifying specific subtypes of ALL, which can be critical for prognosis and treatment.

By analyzing the chromosomal structure and gene rearrangements, the ALL Cytogenetics 1 panel provides essential information for the diagnosis and management of Acute Lymphoblastic Leukemia. It's an indispensable tool that helps doctors to tailor treatment plans according to the genetic profile of the leukemia. If you or a loved one has been diagnosed with ALL or has symptoms suggestive of this disease, this panel could be a crucial step in getting the most effective treatment. It's important to have open communication with the doctor and follow the recommended course of action.

ALL Cytogenetics 1 ( Karyotyping + FISH for BCR-ABL1 + TEL- AML1 + MLL + E2A rearrangement)
₹ 15900 Book Test
Schedule Test in Your Available Time
Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet