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Activated Partial Thromboplastin Time (aPTT) with Mixing Studies

Activated Partial Thromboplastin Time (aPTT) with mixing studies is an essential diagnostic tool in hematology, the medical field dealing with blood disorders. This test provides valuable insights into the functioning of the body's blood clotting mechanism and helps identify potential issues.


  • Test NameActivated Partial Thromboplastin Time (aPTT) with Mixing Studies
  • Sample TypeBlood
  • Preparations RequiredNo specific fasting is required, but it's crucial to inform your healthcare provider about any medications you're currently taking, as these can influence the test results.
  • Report Time6 hours

The aPTT test measures the time taken for blood to clot, focusing on the intrinsic and common clotting pathways. In mixing studies, patient plasma is mixed with normal plasma to see if it corrects the clotting time. This additional step helps differentiate between a factor deficiency (which would be corrected by adding normal plasma) and the presence of an inhibitor (which would not be corrected).

The importance of understanding your clotting efficiency cannot be overstated. An imbalance can lead to excessive clotting, which can cause conditions such as deep vein thrombosis or stroke, or insufficient clotting, leading to excessive bleeding.

Home Sample Collection Process
1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Download Reports
Frequently Asked Questions

The aPTT test with mixing studies helps to differentiate between a clotting factor deficiency and the presence of an inhibitor, like lupus anticoagulant or specific factor inhibitors. This information is crucial for appropriate treatment planning in patients with clotting disorders.

Fasting is not typically required for this test. Always follow your healthcare provider's instructions regarding test preparation.

No specific preparations are needed for the aPTT test with mixing studies. However, make sure to inform your healthcare provider about all the medications you're taking, as they might influence the test results.

This test is usually performed when a standard aPTT test yields prolonged clotting times, and the reason for this prolongation is unclear. Mixing studies can help distinguish between different potential causes.

The aPTT test with mixing studies measures the time it takes for your blood to clot. In the mixing study part of the test, your plasma is mixed with normal plasma to see if the clotting time corrects, helping to determine whether a clotting factor deficiency or an inhibitor is present.

The frequency of this test depends on your individual circumstances, specifically if you've had abnormal aPTT results or if you're undergoing treatment for a clotting disorder.

Normal values for aPTT typically fall between 30 to 40 seconds, but this can vary among laboratories. In a mixing study, a normal result would be the correction of the clotting time when patient plasma is mixed with normal plasma.

Aside from informing your healthcare provider about any medications you're taking, there are no specific precautions needed for this test.

Certain factors, such as medications (e.g., heparin, oral anticoagulants), liver disease, and deficiencies in specific blood clotting factors, can affect the results of the aPTT test and mixing studies.

If the test results are abnormal, suggesting a potential issue with blood clotting, a hematologist should be consulted for further guidance and treatment.

Yes, certain medications, particularly blood thinners like heparin, can significantly influence the test results. Always inform your healthcare provider about any medications you're taking before the test.

Yes, the aPTT test with mixing studies can be performed on pregnant women if necessary. However, physiological changes during pregnancy might slightly influence the test results.

The aPTT test with mixing studies involves a standard blood draw, so risks are minimal. These may include minor pain or bruising at the needle insertion site.

In sum, the aPTT test with mixing studies is a critical instrument for diagnosing and monitoring blood clotting disorders. It offers detailed insights into the functioning of the body's clotting mechanism, aiding in differentiating between clotting factor deficiencies and the presence of inhibitors. As always, the interpretation and understanding of these test results should be facilitated by a trained healthcare provider for the most accurate and beneficial guidance.

Activated Partial Thromboplastin Time (aPTT) with Mixing Studies
₹ 2300
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