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5-Hydroxy Indole Acetic Acid (5-HIAA) - Spot Urine

5-Hydroxy Indole Acetic Acid (5-HIAA) is a metabolite of serotonin, a hormone that plays various roles in the body, including the regulation of mood, appetite, and sleep. An abnormal amount of 5-HIAA in the urine can indicate a carcinoid tumor, a type of slow-growing cancer that can occur in several parts of the body.

  • Test Name5-Hydroxy Indole Acetic Acid (5-HIAA) - Spot Urine
  • Sample TypeUrine
  • Preparations RequiredAvoid foods such as bananas, avocados, pineapples, plums, walnuts, tomatoes, kiwi, and eggplant for 3 days before the urine collection. Avoid alcohol, caffeine, and tobacco during this period.
  • Report Time4 days

Why is this test important?

The 5-HIAA urine test is used to diagnose carcinoid tumors and monitor the effectiveness of treatment for these tumors.

What sample type is required for this test?

This test requires a spot urine sample.

Home Sample Collection Process

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Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
Reporting of the sample at lab
Reporting of the sample at lab
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Frequently Asked Questions

Fasting is not typically required, but you should avoid certain foods and substances for 3 days before the urine collection period.

This test may be recommended if you exhibit symptoms of a carcinoid tumor, such as flushing, diarrhea, wheezing, or rapid heart rate.

This test measures the level of 5-HIAA, a metabolite of serotonin, in your urine.

The frequency of testing depends on your symptoms and the advice of your healthcare provider.

Normal values typically range from 2 to 9 mg/24h, but they may vary between laboratories.

Avoid specific foods and substances, such as bananas, avocados, alcohol, caffeine, and tobacco, for 3 days before and during the urine collection period.

Modifiable Factors: Certain medications and foods can affect the results.

Nonmodifiable Factors: Stress and exercise can also influence 5-HIAA levels.

You should consult an oncologist or endocrinologist if your test results are abnormal.

Management typically involves treating the underlying condition, which may include medication, surgery, or other therapies.

Abnormal results may indicate a carcinoid tumor. Your healthcare provider will guide you on further steps.

Yes, certain medications such as cough syrups, antidepressants, and acetaminophen can affect 5-HIAA levels.

The 5-HIAA urine test is a reliable tool for diagnosing and monitoring carcinoid tumors, but it should be interpreted alongside other clinical findings and tests.

While it may not be possible to prevent conditions that cause abnormal 5-HIAA levels, regular check-ups can help detect any issues early.

After the test, your healthcare provider will discuss the results with you. If your levels are abnormal, further tests may be required.

Yes, stress can cause serotonin levels to rise, which can result in increased 5-HIAA levels.

Yes, exercise can also cause serotonin levels to rise, which can result in increased 5-HIAA levels.

Symptoms may include flushing, diarrhea, wheezing, or rapid heart rate. However, many carcinoid tumors do not cause symptoms until they have spread to other parts of the body.

5-HIAA levels can change rapidly in response to changes in serotonin levels, which can be influenced by diet, stress, exercise, and certain medications.

The 5-HIAA spot urine test is an essential tool in diagnosing carcinoid tumors and monitoring treatment efficacy. Regular communication with your healthcare provider and understanding your test results are key steps in managing your health effectively. Always discuss any concerns or questions you have about your test results with your healthcare provider. Remember, it's vital to maintain a healthy lifestyle, and to keep regular check-ups to ensure early detection of any potential issues.

5 - Hydroxy Indole Acetic Acid (5-HIAA) - Spot urine
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