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Lab Test

Scleroderma Diagnostic Panel II

The Scleroderma Diagnostic Panel II is a comprehensive blood test that screens for the presence of specific autoantibodies, namely ANA - IFA, U1 SmRNP, Anti-Centromere Abs, and Scl-70 IgG Abs. The presence of these antibodies can be indicative of scleroderma and other connective tissue diseases. Let's dive into the various aspects of this diagnostic panel and answer some common questions related to these tests and their implications.


  • Profile NameScleroderma Diagnostic Panel II: ANA - IFA, U1 SmRNP, Centromere Abs, and Scl-70 IgG Abs
  • Sample TypeBlood
  • Preparations RequiredNo special preparation or dietary restrictions are required before providing a blood sample for this test.
  • Report Time3 days

Why is it important to get tested for these antibodies?

Testing for these specific antibodies assists in diagnosing different types of scleroderma and understanding the disease's progression. Early diagnosis leads to timely intervention, potentially improving prognosis and quality of life.

Is fasting required for the Scleroderma Diagnostic Panel II?

No, fasting is not necessary for this test.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

No specific preparation is required. However, it's crucial to inform your healthcare provider about any medications or supplements you are currently taking, as they could influence the test results.

This panel is typically ordered when a patient presents with symptoms suggestive of scleroderma or other connective tissue diseases, such as skin thickening, Raynaud's phenomenon, or joint pain.

The Scleroderma Diagnostic Panel II screens for specific autoantibodies associated with scleroderma and other connective tissue diseases. The presence of these antibodies, along with clinical symptoms, assists in diagnosing and determining the severity and possible progression of the disease.

The frequency of testing depends on your symptoms , disease progression, and your doctor's discretion. If you have scleroderma or another connective tissue disease, regular monitoring might be necessary.

Normal results typically indicate no detectable levels of ANA - IFA, U1 SmRNP, Anti-Centromere Abs, and Scl-70 IgG Abs. However, lab reference ranges may vary.

There are no specific precautions to take before this test, but it's essential to inform your healthcare provider about any medications, supplements, or recent illnesses that could potentially affect the results.

Various factors, such as certain medications, underlying health conditions, and the presence of other autoantibodies, can potentially influence the results of the test.

If your Scleroderma Diagnostic Panel II results are abnormal, it's advisable to consult a rheumatologist or an immunologist for further evaluation and management.

A positive test result indicates the presence of one or more of the antibodies tested, suggesting a possibility of scleroderma or another connective tissue disease. However, further tests and clinical evaluation are needed to confirm a diagnosis.

No, this test requires a blood sample, which should be collected by a healthcare professional in a clinical setting and processed in a specialized lab.

This panel involves a standard blood draw, so risks are minimal. However, some people might experience slight pain, bruising, or infection at the injection site.

A negative test result means no detectable levels of the antibodies were found in your blood. However, a negative result does not necessarily rule out scleroderma or other connective tissue diseases, as these conditions can occur without the presence of these antibodies.

The Scleroderma Diagnostic Panel II is highly reliable when conducted in a specialized lab. However, it is not a standalone test and should be interpreted in conjunction with clinical symptoms and other diagnostic tests.

Understanding scleroderma and the implications of the Scleroderma Diagnostic Panel II can be complex. However, with the right knowledge and medical guidance, you can navigate your health journey confidently.

Treatments for scleroderma focus on managing symptoms and preventing complications. This might involve medications to control immune system overactivity, improve blood flow, manage pain, and address specific organ involvement.

Physical therapy can assist in managing scleroderma symptoms such as joint pain and mobility issues. It helps improve strength and flexibility, thereby enhancing the quality of life.

As of now, there's no known way to prevent scleroderma. It is a disease that arises from a combination of genetic predisposition and environmental triggers.

Scleroderma symptoms may include skin thickening and tightening, Raynaud's phenomenon, joint pain, dry eyes and mouth, digestive issues, and in severe cases, heart or lung problems.

Scleroderma can make daily tasks challenging due to skin tightening, joint pain, and mobility issues. However, with the right medical treatment, physical therapy, and necessary life adaptations, individuals with scleroderma can lead a fulfilling and productive life.

Facing a potential diagnosis of scleroderma can be daunting, but early diagnosis and proper management can significantly improve outcomes and quality of life. Stay informed and proactive about your health, and remember, you're not alone on this journey.

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