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Lab Test

Scleroderma Diagnostic Panel I

Scleroderma Diagnostic Panel I

The Scleroderma Diagnostic Panel I tests for the presence of two types of antibodies: Anti-Centromere antibodies (ACA) and Scl-70 IgG antibodies (anti-topoisomerase antibodies). These antibodies are often associated with different forms of scleroderma, a connective tissue disease. Let's explore this diagnostic panel and answer some of the most frequently asked questions regarding these tests and their implications.


  • Profile NameScleroderma Diagnostic Panel I
  • Sample TypeBlood
  • Preparations RequiredThere are no special preparations or dietary restrictions necessary before providing a blood sample for this test.
  • Report Time2 days

Why is it important to get tested for Anti-Centromere and Scl-70 IgG antibodies?

Testing for these antibodies can assist in diagnosing different types of scleroderma. ACA is usually found in the limited cutaneous form, while Scl-70 IgG antibodies are often found in the diffuse cutaneous form. Early diagnosis can lead to better disease management and improved patient outcomes.

Is fasting required for the Scleroderma Diagnostic Panel I?

No, fasting is not required for this test.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

No specific preparation is necessary for the Scleroderma Diagnostic Panel I.

This test is often ordered when you display symptoms suggestive of scleroderma, such as Raynaud's phenomenon, skin thickening, or other signs indicating a connective tissue disease.

This panel tests for two types of antibodies, ACA and Scl-70 IgG, which are commonly associated with scleroderma. The presence of these antibodies, along with clinical symptoms, can aid in diagnosing and managing the disease.

The frequency of testing is determined by your symptoms and disease progression. Your doctor will provide guidance based on your specific condition.

Normal results typically indicate no detectable levels of ACA and Scl-70 IgG antibodies. However, lab reference ranges may vary.

There are no specific precautions required before this test. It's crucial to inform your healthcare provider of any medications or supplements you are taking, as they could potentially influence the test results.

Certain medications, underlying health conditions, and the presence of other autoantibodies can potentially affect the results of the test.

If your Scleroderma Diagnostic Panel I results are abnormal, you should consult a rheumatologist or an immunologist.

A positive test result indicates the presence of either ACA or Scl-70 IgG antibodies, which are often associated with scleroderma. However, the presence of these antibodies does not necessarily confirm a diagnosis, as they can also be present in other conditions. Further tests and clinical evaluation will be needed.

No, this test requires a blood sample, which should be collected by a healthcare professional and processed in a specialized lab.

This panel involves a standard blood draw, so risks are minimal. However, some people might experience slight pain, bruising, or infection at the injection site.

A negative test result means no detectable levels of ACA and Scl-70 IgG antibodies were found in your blood. However, a negative result does not necessarily rule out scleroderma or other connective tissue diseases.

The Scleroderma Diagnostic Panel I is highly reliable when conducted in a specialized lab. However, it is not a standalone test and should be interpreted in conjunction with clinical symptoms and other diagnostic tests.

Understanding the role and significance of ACA and Scl-70 IgG antibodies in diagnosing scleroderma is crucial in managing the condition effectively.

Treatments focus on managing symptoms and preventing complications. This may involve medications to improve blood flow, suppress the immune system, manage pain, and address specific organ involvement.

Yes, physical therapy can help manage symptoms such as joint pain and mobility issues, improving the quality of life for individuals with scleroderma.

Scleroderma results from a combination of genetic predisposition and environmental triggers, making it currently impossible to prevent its onset.

Symptoms can include Raynaud's phenomenon, thickening and tightening of the skin, joint pain, dry eyes and mouth, digestive problems, and in severe cases, problems with lung or heart function.

Scleroderma can make daily tasks challenging due to skin tightening, joint pain, and mobility issues. However, with appropriate medical treatment, physical therapy, and necessary life adaptations, individuals with scleroderma can lead fulfilling lives.

Navigating through scleroderma can be challenging but with early diagnosis, effective management, and the right support, you can lead a fulfilling life. Remember, your disease doesn't define you - keep living your life with courage, resilience, and positivity.

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