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Lab Test

Ovarian Marker Profile

Ovarian Marker Profile

The Ovarian Marker Profile is a comprehensive blood test that measures several markers associated with ovarian cancer. This profile includes tests for CA125, CEA, CA72.4, HE4, and the ROMA Index. These markers can be elevated in women with ovarian cancer, and their levels can provide valuable information about the presence and progression of the disease.


  • Profile NameOvarian Marker Profile: CA125, CEA, CA72.4, HE4, ROMA Index
  • Sample TypeBlood
  • Preparations RequiredNo fasting is required for this test. Continue your normal diet and hydration levels unless otherwise instructed by your doctor.
  • Report Time6 Hours

Ovarian cancer often goes undetected until it has spread within the pelvis and abdomen, making it more challenging to treat. Early-stage ovarian cancer rarely causes any symptoms, but late-stage ovarian cancer may cause a few nonspecific symptoms that are often mistaken for more common benign conditions. The Ovarian Marker Profile can help detect ovarian cancer at an earlier stage, improving the chances of successful treatment.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

The Ovarian Marker Profile is important for the early detection and monitoring of ovarian cancer. It helps identify abnormal levels of specific markers associated with ovarian cancer, enabling timely intervention and management.

No, fasting is not required for this test. You can maintain your regular diet and hydration levels unless your doctor advises otherwise.

No specific preparation is needed for this test. However, it's important to inform your doctor about any medications or supplements you're taking as they may affect the test results.

This test is typically recommended if you have symptoms suggestive of ovarian cancer, such as abdominal bloating, pelvic pain, or changes in bowel habits. It may also be recommended if you have a family history of ovarian cancer or certain genetic mutations that increase your risk.

This test measures the levels of several markers associated with ovarian cancer, including CA125, CEA, CA72.4, and HE4. The ROMA Index combines the results of the CA125 and HE4 tests to assess the likelihood of ovarian cancer in women presenting with a pelvic mass.

The frequency of this test depends on your individual risk factors and your doctor's recommendations. If you're being treated for ovarian cancer, your doctor may recommend regular testing to monitor your response to treatment.

Normal values can vary based on the laboratory conducting the test. However, your doctor will interpret your results considering your age, sex, and overall health status.

There are no specific precautions for this test. However, it's important to inform your doctor about any medications or supplements you're taking, as they may affect the test results.

Several factors can affect the levels of these markers, including menstruation, pregnancy, certain benign conditions like endometriosis, and other types of cancer. It's important to discuss any potential confounding factors with your doctor.

If your test results are abnormal, you should consult a gynecologist or an oncologist. These specialists have expertise in managing ovarian cancer and can provide guidance on the next steps.

While this test can suggest the presence of ovarian cancer, a definitive diagnosis usually requires additional tests such as imaging studies and a biopsy. However, the Ovarian Marker Profile can provide valuable information to guide further testing and treatment decisions.

If you're pregnant, it's important to discuss this with your doctor. Pregnancy can affect the levels of some markers, potentially leading to misleading results.

This test is typically used in adult women, especially those at risk of ovarian cancer. However, in certain circumstances, it may be used in children, with results interpreted carefully considering their age and development.

Lifestyle changes are unlikely to significantly affect the results of this test. However, maintaining a healthy lifestyle can help reduce the risk of many types of cancer.

Certain medications may affect the levels of these markers. It's important to inform your doctor about all the medications you're taking.

CA125 is a protein that can be elevated in the blood of women with ovarian cancer. However, it can also be elevated in other conditions, so it's used in combination with other tests for a more accurate assessment.

CEA is a protein that can be elevated in certain types of cancer, including ovarian cancer. However, it's not specific to ovarian cancer and can be elevated in other cancers and some benign conditions.

HE4 is a protein that can be elevated in women with ovarian cancer. It's often used in combination with CA125 to calculate the ROMA Index, which can help assess the likelihood of ovarian cancer in women presenting with a pelvic mass.

The ROMA Index is a tool that combines the results of the CA125 and HE4 tests to assess the likelihood of ovarian cancer in women presenting with a pelvic mass. It can help guide further testing and treatment decisions.

While this test is primarily used to detect ovarian cancer, some of the markers measured, such as CEA and CA125, can be elevated in other types of cancer. However, further testing would be needed to diagnose other cancers.

In conclusion, the Ovarian Marker Profile is a comprehensive tool for assessing the risk of ovarian cancer. It can help detect ovarian cancer at an earlier stage, improving the chances of successful treatment. Understanding the test and its components can empower you to take proactive steps towards maintaining your health. Always consult with your doctor for personalized advice based on your health status and test results.

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