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Lab Test

Lung Cancer Panel 2

Lung cancer, specifically non-small cell lung cancer (NSCLC), can often involve various genetic changes that contribute to its development and progression. Recognizing these alterations is crucial as it assists in determining the most effective therapeutic strategy, particularly as some treatments target specific mutations. The Lung Cancer Panel 2 utilizes Fluorescence In Situ Hybridization (FISH) to detect rearrangements in ALK, ROS1, RET genes, and MET gene amplification. These genetic alterations, though less common, are associated with specific subtypes of NSCLC and are targetable by certain treatments.


  • Profile Name Lung Cancer Panel 2
  • Sample Type Tissue
  • Preparations Required No special preparation is needed for this test.
  • Report Time 3 Days

The FISH technique uses fluorescent probes to visualize the rearrangement or amplification of specific regions on the chromosomes where these genes are located. A positive result can lead to more targeted treatment options for the patient and provide valuable prognostic information.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

This test is crucial because it can identify specific genetic changes that could be contributing to the development and growth of your cancer. These changes can affect how the cancer responds to certain treatments, so knowing about them can help your doctor develop a more personalized treatment plan.

A tissue sample is generally obtained through a biopsy procedure, where a small piece of the tumor is removed for testing. The method used to obtain the sample depends on the size and location of the tumor.

Yes, there are no dietary restrictions associated with this test. However, if the biopsy procedure requires anesthesia, you may need to fast prior to the procedure. Your healthcare provider will provide specific instructions based on your individual situation.

The risks associated with this test are primarily related to the biopsy procedure used to collect the tissue sample. These can include infection, bleeding, or complications from anesthesia. The test itself does not pose any risks.

The turnaround time for the Lung Cancer Panel 2 is usually between 1 to 2 weeks. This can vary depending on the laboratory that is processing the sample.

If your test results show a gene rearrangement or amplification, it may mean that you could benefit from certain targeted therapies that are designed to inhibit the activity of the affected genes. Your doctor will discuss the results with you and explain what they mean for your treatment options.

No, this test is not typically used to monitor treatment progress. It's mainly used to help guide initial treatment decisions. Other tests, such as imaging studies or blood tests, may be used to monitor how well your treatment is working.

If no gene rearrangements or amplifications are found, it means that none of the genetic changes tested for in this panel are present in your cancer cells. This doesn't mean your cancer is untreatable — it simply means that other treatment approaches might be more effective.

Although this test can detect rearrangements and amplifications in the ALK, ROS1, RET, and MET genes, it does not identify all possible genetic changes that might be involved in your cancer. Further, this test is typically only useful for people with non-small cell lung cancer, as these genetic changes are not common in other types of cancer.

While the FISH technique used in this test is highly sensitive and specific, there is always a small chance of false positive or false negative results. It's also important to note that a negative result does not exclude the possibility of other genetic alterations not assessed in this panel.

Coverage for this test can vary by insurance provider and policy. It's recommended to check with your insurance company for specific information regarding coverage.

This test is typically ordered by a healthcare provider who is managing your care. It's always recommended to discuss any concerns or questions you have with them.

While the results can provide some prognostic information, many other factors, such as the stage and grade of the cancer, your overall health, and how well the cancer responds to treatment, also play a significant role in your prognosis.

Yes, this test can be performed at any time during your treatment, as the results may help refine your treatment plan.

The reliability of this test is high, but it's important to remember that no test is 100% accurate. Any concerns about the results should be discussed with your healthcare provider.

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