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Lab Test

Infectious Mononucleosis panel

The Infectious Mononucleosis Panel is a diagnostic tool designed to detect the presence of Epstein-Barr Virus (EBV), the primary cause of infectious mononucleosis, also known as mono or the "kissing disease." The panel consists of tests for EBV viral capsid antigen (VCA) IgM and IgG, EBV early antigen (EA) IgG, EBV nuclear antigen (EBNA) IgG, and EBV avidity.


  • Profile Name Infectious Mononucleosis panel
  • Sample Type Serum
  • Preparations Required There are no specific instructions like fasting or restrictions on water consumption before the test.
  • Report Time 3 days

Epstein-Barr Virus is a type of herpesvirus, which most people become infected with at some point in their lives. In most cases, EBV causes a mild illness or no symptoms at all. However, if a person is infected with the virus during adolescence or young adulthood, it can lead to infectious mononucleosis, characterized by symptoms like fever, sore throat, swollen lymph nodes, and fatigue

The different antibodies in the panel help distinguish between a current, recent, or past EBV infection, thus helping guide treatment decisions

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

The Infectious Mononucleosis Panel is vital for diagnosing infectious mononucleosis caused by EBV. Since the symptoms of mono are similar to other conditions like strep throat and the flu, the panel helps confirm the diagnosis, enabling appropriate treatment.

No, fasting is not required for the Infectious Mononucleosis Panel.

No specific preparation is needed for the test. You should inform your healthcare provider of any medications you're taking as some may affect the test results.

If you are experiencing symptoms suggestive of mono, like fatigue, fever, sore throat, and swollen lymph nodes, especially if they persist for more than a week, your healthcare provider may recommend the Infectious Mononucleosis Panel.

The panel provides information about whether you have a current, recent, or past EBV infection. Each of the antibodies in the panel gives specific information about the stage of the infection.

The frequency of testing depends on your symptoms and medical history. Your healthcare provider will recommend when and how often you should get tested.

Normal values would show no detectable levels of the antibodies associated with a current or recent infection (EBV VCA IgM, EBV EA IgG, and low EBV VCA IgG). However, most adults will show detectable levels of EBNA IgG and possibly EBV VCA IgG, indicating a past infection.

Before the test, inform your doctor about any medications you're taking as some may affect the test results. After the test, no specific precautions are required unless your healthcare provider instructs otherwise.

The presence of EBV antibodies in the serum is indicative of an EBV infection. Factors that can affect this include the stage of the infection, your immune response, and possibly certain medications.

Modifiable factors include medications that suppress the immune system, which can affect your body's response to the virus. Non-modifiable factors include age, as adolescents and young adults are more likely to develop symptoms if infected with EBV.

You should consult with a healthcare provider familiar with infectious diseases, typically your primary care provider or an infectious disease specialist.

The panel involves a standard blood draw, which can cause slight discomfort but is generally not considered painful.

The risks are minimal and are associated with the blood draw, including slight pain, bruising, or infection at the puncture site.

Yes, a mono spot test can be used as a quicker, less precise method of diagnosing mono. However, it cannot distinguish between current, recent, or past infections like the Infectious Mononucleosis Panel.

You should discuss all medications you're taking with your healthcare provider, as some may affect the test results.

Yes, you can typically resume normal activities immediately after the blood draw.

The turnaround time varies, but results are typically available within 1-3 days.

Yes, it is possible. The test is most reliable a few weeks after infection. If your symptoms persist, your healthcare provider might recommend retesting or additional tests.

Your healthcare provider might order the test again if symptoms persist or return, or to monitor the progression of the infection.

While there's no vaccine to prevent mono, avoiding close contact with people who have the infection can reduce the risk.

In conclusion, the Infectious Mononucleosis Panel is an essential diagnostic tool for detecting and monitoring mono. The information it provides enables healthcare providers to deliver timely and appropriate treatment, which can significantly improve patient outcomes.

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