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Lab Test

HIV 1 Monitoring Profile

Human Immunodeficiency Virus (HIV) is a viral infection that gradually damages the immune system and can lead to Acquired Immunodeficiency Syndrome (AIDS) if not managed properly. Monitoring the progress of the disease and effectiveness of the treatment is crucial in HIV management, which is the primary goal of the HIV 1 Monitoring Profile.


  • Profile Name HIV 1 Monitoring Profile
  • Sample Type Blood
  • Preparations Required No specific preparations are required for this test. Continue with the regular diet and medications unless advised otherwise by your healthcare provider.
  • Report Time 2 days

The HIV 1 Monitoring Profile consists of two key tests: the CD4 and CD8 Lymphocyte Subsetting and the HIV-1 RNA Quantitative PCR.

The CD4 and CD8 Lymphocyte Subsetting test measures the count of two key types of immune cells, CD4 and CD8 T cells. These cell counts provide insight into how well the immune system is functioning. In HIV infection, the CD4 T cell count usually decreases, making the person more vulnerable to opportunistic infections. Conversely, the CD8 T cell count may increase as these cells are involved in fighting viral infections.

The HIV-1 RNA Quantitative PCR, also known as the viral load test, measures the amount of HIV RNA (genetic material of the virus) in the blood. This test is useful to assess how actively the virus is reproducing in the body. A high viral load typically indicates active viral replication and may suggest a higher risk of disease progression.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

This test is essential to monitor the progress of HIV infection, assess the immune system's response, and evaluate the effectiveness of antiretroviral therapy (ART).

No specific preparation is needed for this test. Continue your regular diet and medication unless advised otherwise by your healthcare provider.

This test is typically done at the time of diagnosis, before starting ART, and then regularly during treatment to monitor the disease's progress and treatment effectiveness.

The CD4 and CD8 Lymphocyte Subsetting test measures the number of CD4 and CD8 T cells in the blood, while the HIV-1 RNA Quantitative PCR test measures the amount of HIV RNA in the blood.

A high CD4 count indicates a healthier immune system. However, in the context of HIV, a high CD4 count is relative and generally means the count is higher than it would be with unchecked HIV progression.

A high viral load typically indicates active viral replication, suggesting that the disease may progress faster. It could also indicate that the antiretroviral therapy is not effectively suppressing the virus.

Yes, other infections, vaccination, or stress can temporarily affect CD4 counts and the viral load.

A high viral load may indicate that your current treatment regimen isn't effectively controlling the virus. Your healthcare provider might consider adjusting your treatment.

Recent studies suggest that individuals with an undetectable viral load due to successful antiretroviral therapy are significantly less likely to transmit the virus to others. However, precautions should always be taken to prevent HIV transmission.

The normal range can vary, but generally, a normal CD4 count ranges from 500 to 1,200 cells/mm³, and a normal CD8 count is typically between 150 to 1,000 cells/mm³.

If your CD4 count is low, your healthcare provider will likely discuss starting or modifying your antiretroviral therapy and may recommend prophylactic treatments for certain opportunistic infections.

The frequency of testing can vary depending on the stage of your HIV infection, your overall health, and your treatment regimen. Typically, monitoring tests are done every 3 to 6 months.

While HIV is a chronic illness, with proper treatment and care, individuals with HIV can live long and healthy lives.

The test involves a blood draw, which may cause slight discomfort.

As of now, there's no cure for HIV. However, effective antiretroviral therapies can control the virus and prevent progression to AIDS.

The HIV 1 Monitoring Profile plays a significant role in managing HIV infection. It helps gauge the disease's progression, assess the immune system's function, and monitor the effectiveness of the treatment. Remember, early detection and regular monitoring are key to managing HIV effectively. As such, it is crucial to have open communication with your healthcare provider and adhere to the recommended testing schedules.

While at-home testing options are available for initial HIV screening, the tests in the HIV 1 Monitoring Profile require blood samples to be collected and processed in a laboratory setting.

CD4 cells, also known as T cells or helper cells, are a type of white blood cell that plays a crucial role in maintaining the immune system. HIV targets and destroys these cells, which leads to a weakened immune response.

While at-home testing options are available for initial HIV screening, the tests in the HIV 1 Monitoring Profile require blood samples to be collected and processed in a laboratory setting.

CD4 cells, also known as T cells or helper cells, are a type of white blood cell that plays a crucial role in maintaining the immune system. HIV targets and destroys these cells, which leads to a weakened immune response.

Yes, it's possible for a person to have a normal CD4 count and still be infected with HIV, especially in the early stages of infection. Regular monitoring and clinical assessment are necessary for effective management of the condition.

ART is designed to suppress the replication of the HIV virus, thereby reducing the viral load and allowing the immune system to recover and increase the CD4 count. If the therapy is effective, over time, the viral load should decrease and the CD4 count should increase.

Depending on your health and treatment plan, your healthcare provider might recommend additional tests, such as resistance testing, other blood tests to monitor your overall health, and tests for opportunistic infections.

Not necessarily. While CD8 cells are important in fighting off viral infections, a higher CD8 count in the context of HIV infection can indicate an active immune response to the virus.

The ratio of CD4 to CD8 cells can fluctuate in different diseases and conditions. In HIV, a high CD4 count is generally a positive sign, indicating a stronger immune system. However, these counts should be interpreted in the context of other health information and lab results.

If your viral load continues to increase despite treatment, it might mean that your current treatment regimen is not effective, and the virus is multiplying in your body. It is crucial to consult with your healthcare provider about alternative treatment strategies.

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