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Celiac Profile Test

The Celiac Profile Test is a group of blood tests used to diagnose celiac disease, an autoimmune disorder triggered by gluten ingestion. Gluten is a protein found in wheat, barley, and rye. In people with celiac disease, gluten ingestion leads to inflammation and damage in the small intestine.


  • Profile Name Celiac Profile Test
  • Sample Type Blood
  • Preparations Required No specific preparation is required before the test
  • Report Time 6 hours

This profile includes testing for Tissue Transglutaminase (TTG) IgA antibodies, Gliadin IgG and IgA antibodies, and Endomysial antibodies (EMA). These markers are essential in identifying the immune response that leads to intestinal damage in celiac disease. This guide will answer frequently asked questions about the Celiac Profile Test.

Home Sample Collection Process

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2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

This test is critical for diagnosing celiac disease. If you have symptoms like diarrhea, abdominal pain, weight loss, or signs of malnutrition, your doctor may recommend this test. Timely diagnosis can prevent complications like malnutrition, osteoporosis, infertility, and certain types of lymphoma.

No, fasting is not necessary for the Celiac Profile Test.

No specific preparation is required for this test. However, it's crucial to inform your doctor about any medications, supplements, or ongoing treatments, as certain substances might interfere with the test results.

If you have symptoms suggestive of celiac disease or a close relative with celiac disease, your doctor may recommend this test. Symptoms include diarrhea, abdominal pain, unexplained weight loss, and fatigue.

The test measures the level of specific antibodies in your blood. High levels of these antibodies indicate that your immune system is reacting to gluten in a way that damages your small intestine, suggesting the presence of celiac disease.

If you're diagnosed with celiac disease, your doctor may recommend this test at diagnosis and periodically afterward to monitor your response to a gluten-free diet.

Normal values may vary depending on the laboratory but generally, negative results for TTG IgA, Gliadin IgG and IgA, and Endomysial antibodies indicate no celiac disease. However, your doctor will interpret the results in the context of your symptoms and medical history.

There are no special precautions needed for this test. However, it's important to inform your doctor about any medications or dietary supplements you're taking.

Your diet is the primary modifiable factor. If you're already following a gluten-free diet, it could lower the antibody levels and affect the test results. It's important to discuss your diet with your doctor before the test.

Genetics plays a significant role in developing celiac disease. However, having the genes associated with celiac disease doesn't guarantee that you'll have the disease. Other factors like age, sex, and race can also influence the risk of celiac disease but are not modifiable.

If your test shows an abnormal result, you should consult a gastroenterologist. They can interpret your results, discuss your diagnosis, and guide you on the next steps.

The sample for this test is collected through a standard blood draw.

Yes, you can take this test during pregnancy. However, it's important to inform your doctor about your pregnancy status before any test or procedure.

The risks are minimal and related to the blood draw. These could include slight pain or bruising at the needle site, fainting, or infection.

While foods don't typically affect the test results, following a gluten-free diet before the test can lower the antibody levels and impact the results. Some medications may also interfere with the results. It's essential to inform your doctor about any medication or diet regimen you're following.

The test involves a standard blood draw, which may cause slight discomfort or pain at the puncture site.

No, stress does not typically affect the results of the Celiac Profile Test.

This test can be performed as an outpatient procedure. However, if you're already in the hospital for related symptoms or complications, it might be done during your hospital stay.

Results are typically available within 2 to 5 days, but the timing may vary depending on the laboratory.

While the Celiac Profile Test is specifically designed to diagnose celiac disease, abnormal results can occasionally be seen in other autoimmune conditions or liver diseases. However, further tests are needed for a definitive diagnosis of these conditions.

The Celiac Profile Test is a vital tool in diagnosing and managing celiac disease. Remember, you and your doctor are partners in your health journey. By understanding the importance of this test and how it fits into your overall health plan, you can take an active role in managing your health. Always consult your doctor if you have any questions or concerns about the test, the results, or your treatment plan.

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